Syllabus Information

1. General information

Physiology I A subject with essential information to follow the study of biophysics and systemic physiology. The aim is that the student knows the most useful general and tissue functions of the human body applied in Medicine: 1) Study of biorhythms and oxidative stress.

2) Cellular compartments, substance transport.

3) Bioelectric potentials in excitable cells.

4) Cellular communication.

5) Bases of human nutrition

6) Functions of the muscle

These approaches are aligned with the goals of the United Nations 2030 Agenda for Sustainable Development (SDGs):  3 (Health and well-being), 4 (Quality education) and 5 (Gender equality)

https://www.un.org/sustainabledevelopment/es/,

2. Learning results

2.1. Learning Results

In order to pass this subject, the student must demonstrate that they knows how to define, analyse, apply and explain the following learning results on:

1. The field of study of Physiology, General Physiology, Special Physiology and Biophysics.

2. Biological servo systems and their characteristics.

3. Biological rhythms and their characteristics.

4. The main free radicals, antioxidant mechanisms in living organisms and their characteristics.

5. The concept of oxidative stress.

6. Biological liquids and their characteristics.

7. The compartments of the organism and their characteristics.

8. The concept of pH, its values in biological fluids, buffers and their characteristics.

9. The general principles of the transport of substances in biological membranes and their characteristics.

10. The mechanisms of intercellular information transmission and their characteristics.

11. The mechanisms of information transmission in excitable tissues, and their characteristics.

12. The processes of genesis, conduction and transmission of the action potential.

13. The main neurotransmitters used in the vegetative nervous system.

14. The mechanisms of hormonal action and their characteristics.

15. The physical basis of bioenergetics.

16. The physical and functional basis of human nutrition.

17. Nutritional parameters in humans in special physiological situations.

18. Muscle contraction.

19. Differences in contraction in skeletal, smooth and cardiac muscle.

2.2. Importance of learning results

The importance of the learning results obtained in this subject lies in the ability to give a good foundation to the functional and pathophysiological knowledge necessary in the training of a physician

3. Syllabus

Theory: Physiology I

Concept and field of study and role of physiology; homeostasis, biorhythms; free radicals; oxidative stress and antioxidants; transport of substances; bioelectrical potentials: genesis, conduction and transmission of action potentials; synapses; neurotransmitters and receptors; autonomic nervous system; organic fluids and compartments; pH and its regulation; mechanisms of hormonal action; bioenergetics; normal nutrition and in special situations; skeletal, smooth and cardiac muscle

Practices:

Learning workshop, aging, transport and permeability, bioelectric potentials, action potential transmission, study of a cellular function or concept map, nutritional status evaluation, diet assessment, muscle contraction, muscle metabolism in exercise.

4. Academic activities

1- Theoretical class (1,6 ECTS): 40 hours

2- Laboratory practices, computer simulations, seminars, problems, and cases (0.8

ECTS): 20 hours

All students will be informed about the risks that may be involved in the practices of this subject, as well as if dangerous products are handled and what to do in case of accident, and must sign the commitment to comply with the work rules and safety to be able to perform them. For more information, consult the information for students of the Occupational Risk Prevention Unit:

http://uprl.unizar.es/estudiantes.html

3- Directed work (0,96 ECTS): 24 hours

4- Evaluation (0,24 ECTS): 6 hours

5- Study (2,4 ECTS) : 60 hours

5. Assessment system

Minimum grade required 5 out of 10.

The evaluation will have 3 parts: 1/ Written exam (85%) will explore theoretical and practical learning results; 2/ tutored work (10%); 3/ Attendance to practices (5%).

If a passing grade (5 out of 10) is not achieved in the written exam, the grade in the minutes will be the grade obtained in the exam, without weighting with tutored work or attendance to practices. Honours will be awarded following the order of final grade (100%).

1/Written exam (85% of the final grade): First and second call

• Contents: Theory and practice programs
• 75 minutes
• 35 multiple-choice test questions (5 options, one correct). Of these, 5 will correspond to practices. Pass:

(5) with 24 points. 50% qualification.

• 3 questions (development, problems or short questions). 50% qualification.
• Students who for justified reasons do not show up for the comprehensive exam, will take an exam with 4 developmental questions, divided in problems or short questions, 15 minutes/question.

2/ Tutored work (10% of the final grade): It will only be added upon passing the written exam. In case of failure to pass the subject, grades higher than 5 in the tutored work will be kept for three calls.

3/ Attendance to practices (5% of the final grade): punctuality, participation, behaviour, etc. will be valued. Students who have more than two unjustified absences will take a practical exam.